Advanced Science
Accelerate Scientific Discovery at Scale
We build and deploy high-performance bioinformatics pipelines — from genome alignment to multi-omics integration — so your research team can focus on biology, not infrastructure.
What We Deliver
Our Bioinformatics Capabilities
Genome Alignment & Variant Calling
WGS/WES short-read and long-read alignment, SNP/indel calling, and structural variant detection pipelines.
Transcriptomics & RNA-Seq
Bulk RNA-Seq, scRNA-Seq, and spatial transcriptomics workflows from raw FASTQ to differential expression.
Multi-Omics Integration
Proteomics, metabolomics, and epigenomics data harmonisation for pathway and network analysis.
Pipeline Automation & HPC
Nextflow and Snakemake workflows deployed on AWS Batch, SLURM, or cloud HPC for reproducible execution.
Clinical Reporting & LIMS Integration
Structured variant reports meeting CAP/CLIA requirements with direct LIMS and EHR feed integration.
Biological Data Visualisation
Custom R Shiny and React dashboards for genome browsers, pathway maps, and cohort-level analytics.
Built for Growth, Not Just Delivery
Measurable outcomes from every engagement
10x
Faster pathway analysis vs naive scripts
5+
NGS pipelines
99%
Reproducibility across pipeline runs
100%
Pipelines version-controlled and containerised
How We Work
From Idea to Impact
Requirements
Define the biological question, data modalities, reference genomes, and regulatory context before any code is written.
Pipeline Design
Select tools, choose workflow manager (Nextflow/Snakemake), and map the DAG from raw data to validated outputs.
Validation
Run against benchmark datasets, compare to gold-standard call sets, and validate sensitivity and specificity metrics.
Deployment
Containerise with Docker/Singularity, deploy to cloud HPC or on-prem cluster, and configure CI for regression testing.
Documentation
Deliver full pipeline documentation, parameter guides, and training so your team can operate and extend the system independently.
What You Get
Key Deliverables
- Genomics, WGS/WES variant discovery, comparative genomics, and precision medicine analytics
- Transcriptomics, RNA-Seq, scRNA-Seq, microarray, epigenomics, and pathway analysis workflows
- Proteomics, metabolomics, biological data asset engineering, and multi-omics integration platforms
- AI-driven molecular modeling, drug discovery, 3D structural biology, and publication support systems
Proven Outcome
10x reduction in compute time for high-throughput pathway analysis
Tech Stack
Technologies We Work With
Got Questions?
Frequently Asked Questions
Do you support both short-read (Illumina) and long-read (ONT/PacBio) data?
Yes. We work with Illumina short reads for high-accuracy variant calling and long reads from Oxford Nanopore and PacBio for structural variant detection and phasing.
Can you work with sensitive clinical genomics data?
Yes. We architect pipelines with encryption at rest and in transit, audit logging, and de-identification workflows compatible with HIPAA and GDPR requirements.
Cloud HPC vs on-prem cluster — which should we use?
Cloud (AWS Batch, Google Life Sciences) is better for burst compute and cost-at-scale. On-prem is preferred when data cannot leave your network due to compliance. We design for both and can build hybrid architectures.
Can you integrate with our existing LIMS?
Yes. We have built integrations with LabVantage, LabWare, and custom LIMS systems, passing sample metadata and pipeline results bidirectionally via REST APIs.
Still have questions? Contact us
Let's Build Together
Ready to Transform Your Business?
Let's build innovative solutions that drive growth, reduce costs, and unlock new opportunities for your business.